Veripath Test Directory

Epic Test Name FISH, C-MET
Synonyms C-MET FISH
Description Fluorescence in situ hybridization (FISH) is performed to detect the C-MET gene amplification, most commonly observed in lung cancer.
Specimen Requirements 
Container Two unstained positively charged slides cut at 4 microns and one H&E stain slide.
Specimen Type FFPE (Formalin Fixed Paraffin Embedded Tissue)
Preferred Collection Volume
Minimum Collection Volume
Collection Instructions
Specimen Handling
Rejection Criteria Cases without H&E slide.
Methodology A dual color fluorescent labeled DNA probe for the C-MET gene, at chromosome band 7q31.2, is hybridized to unstained interphase nuclei on a slide. 200 cells are evaluated to determine whether the signals are amplified.
Reference Range See interpretive report.
CPT Code(s) 88271X2,88275,88291.
Department Cytogenetics
Contact Information Cytogenetics Lab: (214) 648-0975, Customer Service: (214) 645-7057 or Toll Free (877) 887-8136
Turn Around Time6 working days after specimen arrival in Cytogenetics Lab
Performed 3 times a week
Performed by Cytogenetics
Updated/Reviewed 12/12/2016