Veripath Test Directory

Components IgG, IgM, IgA
Synonyms ACL, ACLA, Anticardiolipin Antibodies.
Description Antiphospholipid antibodies are associated with recurrent thrombosis, both venous and arterial, and recurrent fetal loss. They are very heterogeneous, detected by clotting assays (often called lupus anticoagulants) or immunologic assays. Cardiolipin is a negatively charged phospholipid which is used in an ELISA Assay to detect antibodies (IgG, IgM, and IgA) in the patient's serum.
Specimen Requirements 
Container Plain red or serum separator collection tube
Specimen Type Blood
Preferred Collection Volume 5 mL
Minimum Collection Volume Adult: 2 mL, Neonates : 2 mL
Collection Instructions Draw blood in a plain red or serum separator collection tube. Specimen Handling:
In-house patients, transport at room temperature.
Specimen Handling Outside clients, follow collection instructions and the steps below:
1. Spin plain red or serum separator tube. Separate serum from cells as soon as possible.
Place serum in plastic tube. (Glass tube unacceptable).
2. Transport frozen.
Rejection Criteria Hemolysis, clotted, short sample, >4 hrs old (if not refrigerated) or >72 hours (if not frozen).
Methodology ELISA
Reference Range IgG ≤ 13 GPL; IgM ≤ 9 MPL; IgA ≤16 APL.
CPT Code(s) 86147 x 3
Department Hemostasis/Coagulation
Contact Information Hemostasis Lab; 214-633-4959 Customer Service: 214-633-0400, Toll Free 1-877-887-8136.
Turn Around Time1-7 days
Performed Mondays
Performed by Hemostasis Lab
Updated/Reviewed 07/23/2016