Veripath Test Directory

Components IgG, IgA, and IgM
Synonyms Anti· B2· Giycoprotein I
Description Anti-Beta 2 Glycoprotein I is one of the clinically signficant anti-phospholipid antibodies. Anti-phospholipid antibodies are heterogenous group of immoglobulins that have been associated with increased risk for recurrent aterial and venous thrombotic events, thrombocytopenia, and fetal loss. These manifestations are the main features of the anti-phospholipid syndrome. Beta 2 Glycoprotein I antibodies have been shown to be more specific for thrombosis than anticardiolipin antibodies in patients wit anti-phospholipid syndrome. An ELISA assay is utilized to detect antibodies directed against Beta-2 Glycoprotein I in the patient's serum.
Specimen Requirements 
Container Red top or serum separator collection tube
Specimen Type Blood
Preferred Collection Volume 5 mL
Minimum Collection Volume Adult: 2 mL, Neonates : 2 mL
Collection Instructions Draw blood in a plain red or serum separator collection tube. Specimen Handling:
In-house patients, transport at room temperature.
Specimen Handling Outside clients, follow collection instructions and the steps below:
1. Spin plain red or serum separator tube. Separate serum from cells as soon as possible.
Place serum in plastic tube. (Glass tube unacceptable).
2. Transport frozen.
Rejection Criteria Hemolysis, clotted, short sample, >4 hrs old (if not refrigerated) or >72 hours (if not frozen).
Methodology ELISA
Reference Range IgG ≤ 8 GPS -- IgM ≤ 14 MPS -- IgA ≤ 18 APS
CPT Code(s) 86146 x 3
Department Hemostasis/Coagulation
Contact Information Hemostasis Lab; 214-633-4959 Customer Service: 214-633-0400, Toll Free 1-877-887-8136.
Turn Around Time1-7 days
Performed Tuesday
Performed by Hemostasis
Updated/Reviewed 07/23/2016